Here are a couple of interesting spamassasin rule sets:
Here is some related help...
"Installing and configuring Exim 4 on Debian" - Nice step by step how-to.
Here is something that made a huge difference on my spam set:
SURBL - Spam URI Realtime Blocklists
This is similar to an RBL, but instead of looking at an email source it looks at URIs found in the email body.